Interactions of the amphiphiles arbutin and tryptophan with phosphatidylcholine and phosphatidylethanolamine bilayers in the dry state

Table 1 Gel to liquid-crystalline phase transition temperatures (T _m in °C) of dry liposomes in the absence (pure) or presence of Arb, Glc, Trp, or Gly

Lipid composition	Pure	Arb	Glc	Trp	Gly
100% EPC	40	−24	−24	20	40
100% EPE	−3	−18	−18	5	−2
50% EPE/	0	−22	−15	20	2
50% EPC	0	−22	−15	20	2
50% EPE/	48	−20	−13	29	51
50% DMPC	48	−20	−13	29	51

T_m was determined by FTIR spectroscopy as the midpoint of melting curves obtained as shown in Figure 1. Data for the pure lipids are identical to those published previously [23].

ISSN: 2046-1682