|
domain
|
mutated site
|
mutation
|
TΔSphi
|
TΔSpsi
|
TΔSomega
|
TΔSsidechain
|
TΔStotal
|
|---|
|
Rad53-FHA1
|
1
|
pT→pS
|
0.18
|
0.29
|
0.03
|
1.39
|
1.91
|
|
Rad53-FHA1
|
1
|
pT→pS
|
0.37
|
0.37
|
0.14
|
1.26
|
2.16
|
|
Dun1-FHA
|
1
|
pT→pS
|
-0.25
|
-0.08
|
0.00
|
0.72
|
0.45
|
|
Ki67-FHA
|
1
|
pT→pS
|
0.25
|
0.32
|
0.14
|
1.50
|
2.23
|
|
Dun1-FHA
|
2
|
pT→pS
|
0.10
|
-0.01
|
0.00
|
1.03
|
1.12
|
|
Ki67-FHA
|
2
|
pS→pT
|
-0.04
|
-0.06
|
0.01
|
-0.47
|
-0.57
|
|
BRCT
|
1
|
pS→pT
|
-0.08
|
0.01
|
0.00
|
0.35
|
0.28
|
|
WW
|
1
|
pS→pT
|
-0.15
|
-0.01
|
-0.12
|
-0.71
|
-1.01
|
- Configuration entropy changes (kcal/mol) for phi, psi, omega and sidechain dihedrals of phosphoresidue in the wild-type and mutants.
