Skip to main content
Figure 8 | BMC Biophysics

Figure 8

From: Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase

Figure 8

A conserved conformational switching mechanism centered on β’ D784 about 20 Å from H1. The substrate ATP, Mg-I and Mg-II (green) are in space-filling representation. Proposed switch residues are in stick representation. The two orientations of D784 observed in simulations of closed and open trigger loop RNAP TECs are indicated with blue arrows. Some atomic interactions are indicated with blue lines or emphasized with blue circles.

Back to article page

BMC Biophysics

ISSN: 2046-1682

Contact us