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Figure 4 | BMC Biophysics

Figure 4

From: A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

Figure 4

Persistent long-range contacts mapped onto structure of rhodopsin. Persistent edges at penalty 140 for the top 10 residues are mapped onto the rhodopsin structure (PDB id 1U19). The residues forming the edges are represented as yellow spheres. The edges are TM-TM (cyan), IC-TM (dark green), EC-RT (red), RT-TM (blue), IC-RT (green) and RT-RT (orange), where EC, IC, TM and RT represent residues in extracellular, intracellular, transmembrane and RT (ligand binding) domains, respectively. The image was generated using PyMOL (Version 0.99rc6; http://pymol.org/pymol)

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