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Table 1 GPCR summary table

From: A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

Receptor PDB IDs [number of structures] Ligands
Bovine Rhodopsin (BR) 1 F88, 1GZM, 1HZX, 1JFP, 1L9H, 1LN6, 1U19, 2 G87, 2HPY, 2I35, 2I36, 2I37, 2J4Y, 2PED, 3C9L, 3C9M, 3CAP, 3DQB [18] RT, Ligand free
Squid Rhodopsin (SR) 2Z73, 2ZIY [2] RT
Turkey β1 adrenergic receptor (β1AR) 2VT4, 2Y00, 2Y01, 2Y02, 2Y03, 2Y04 [6] Cyanopindilol, Dobutamine Carmoterol, Isoprenaline Salbutamol
Human β2 adrenergic receptor (β2AR) 2R4R, 2R4S, 2RH1, 3D4S, 3KJ6, 3NY8, 3NY9, 3NYA, 3P0G, 3PDS [10] Carazalol, Timolol, ICI 118,551, (molecule from Kolb et al., 2009), Alprenolol, BI-167107, FAUC50
Human A2A adenosine receptor (A2A) 3EML [1] ZM241385
Human chemokine receptor (CXCR4) 3ODU, 3OE0, 3OE6, 3OE8, 3OE9 [5] IT1t, CVX15
Human dopamine D3 receptor (D3R) 3PBL [1] Eticlopride
  1. Summary of structural information available on GPCRs as of January 2011. While all ligands are small molecules, CVX15 (in bold) is a peptide.