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Table 8 Residues in AT1R that are homologous top ranking edge forming residues in rhodopsin

From: A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

Ballesteros-Weinstein numbering

Rhodopsin residues

ATR1 residues

EC (N-Terminus)

Y29

K20

1.39

M44

Y35

1.43

I48

F39

IC1

K67

M57

IC1

L72

A63

2.57

G90

L81

2.58

F91

P82

3.28

E113

A104

3.29

G114

S105

3.32

A117

V108

3.35

G120

N111

3.37

E122

Y113

3.41

W126

F117

IC2

C140

V131

IC2

F148

R140

EC2

S176

N168

EC2

Y178

F170

EC2

S186

V179

EC2

E196

S189

5.42

M207

K199

5.46

H211

G203

IC3

Q237

--

IC3

Q244

K232

IC3

E247

N235

6.52

A269

Q257

6.55

A272

T260

7.38

P291

T287

7.39

A292

I288

7.40

F293

C289

7.43

K296

Y292

IC (C-Terminus)

C316

Y312