Figure 3
From: Physical constraints on the establishment of intracellular spatial gradients in bacteria
Source and sink saturation does not significantly reduce the R ∼ P gradient except in very stringent saturation conditions. A) Schematic of localization of source and sink. B) Mathematical modeling of the R ∼ P concentration near the phosphatase pole [R ∼ P]phosnormalized to the total response regulator concentration [Rtot] for varying σ p , and σ k  = 10 and 100/s. C) The effective phosphatase rate σp,eis high enough to outcompete diffusion except when the number of enzymes is less than 10% than of the substrate.