Skip to main content
Figure 1 | BMC Biophysics

Figure 1

From: Molecular dynamics simulations indicate an induced-fit mechanism for LSD1/CoREST-H3-histone molecular recognition

Figure 1

Structural biology of LSD1/CoREST complex. The crystal structure of LSD1/CoREST complex bound to the H3-histone N-terminal tail (PDB entry 2V1D). LSD1 (orange) consists of the amine oxidase (AO) domain, SWIRM (red), and Tower domains. CoREST (cyan) consists of the linker and SANT2 domains. The figure highlights the first sixteen N-terminal residues of the H3-histone substrate (blue mesh surface), the H3-tail binding region (yellow) and the FAD cofactor (green spheres).

Back to article page

BMC Biophysics

ISSN: 2046-1682

Contact us