Drop drying on surfaces determines chemical reactivity - the specific case of immobilization of oligonucleotides on microarrays

Table 1 Comparison of oligonucleotide immobilization on 2D and 3D surfaces

Comparison of immobilization efficiencies of oligonucleotides with and without amine linker on 2D epoxy and 3D hydrogel slides for arrays spotted from nL drop volumes, pipetting μL volumes, and in liquid phase for probe concentration in the low μM range.
^(a)hydrogel layer remains wet after drop drying.

ISSN: 2046-1682