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Table 1 Biophysical property of Treg cells by detection of AFM

From: AFM detection of biophysical characteristics of specific regulatory T Cells after allogeneic hematopoietic stem cell transplantation

Groups Width (W) (μm) Peak (H) (nm) Ra (nm)
Total CD4 + CD25+ cells 12.04 ± 0.24 3.95 ± 0.27 250.83 ± 82.39
Total CD4 + CD25- cells 10.23 ± 1.54 3.27 ± 0.32 110.45 ± 22.11
P values* < 0.001 < 0.001 < 0.001
CD4 + CD25+ with GVHD 11.96 ± 0.17 3.85 ± 0.14 191.33 ± 75.22
CD4 + CD25+ without GVHD 12.12 ± 0.13 4.12 ± 0.21 311.67 ± 18.45
P values* 0.032 < 0.001 < 0.001
  1. Ra: average roughness Ra= 1 / N ∑ n = 1 N Z n − Z ¯ ; Z ¯ : given by the average height within the included areas defined by a region group Z ¯ = 1 / N ∑ n = 1 N Z n ; The Z is the height profile line based on the surface.
  2. *Compared by the Welch test.
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BMC Biophysics

ISSN: 2046-1682

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