Figure 2

Electrostatic potential on the molecular surfaces. (a) Actin, (b) Human septin, and (c) Yeast septin. Half of the biological units of the septins (Sept7-Sept6-Sept2 for human septin and Cdc11-Cdc12-Cdc3-Cdc10 for yeast septin) are shown here for simplicity. The blue regions shown in the bottom view of the septins are the polybasic regions, which are assumed to be the binding surface to the membrane in the simulation.