Skip to main content
Fig. 6 | BMC Biophysics

Fig. 6

From: Structure and domain dynamics of human lactoferrin in solution and the influence of Fe(III)-ion ligand binding

Fig. 6

Effective diffusion coefficient Deff of iron free Lf and iron saturated Lf at pD5: in the initial slope (red dots) and the long time behavior (blue: circles 50 ns < t < 200 ns, squares: 20 ns < t < 80 ns, triangle: 12 ns < t < 50 ns). The diffusion constant obtained from DLS (black cross) is shown as well as the expected rigid body diffusion Deff(Q) = D0(Q)H/S(Q,c) for the open-open and closed-closed model respectively in the initial slope (black lines). D0(Q) calculated from equ. 1. Broken lines show the slope analysis (initial and long time) of the fitted model, which agrees well with the experimental finding. The translational diffusion contribution DT(Q) = D0HT for Q > 0.1 is 1.7 Å2/ns for iron free Lf and 1.74 Å2/ns for iron saturated Lf pD 5

Back to article page