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Table 2 Variables employed in the PAPm to evaluate the time dependent mass diffusion of IP3 along one dimension

From: Synaptic neuron-astrocyte communication is supported by an order of magnitude analysis of inositol tris-phosphate diffusion at the nanoscale in a model of peri-synaptic astrocyte projection

Variable

Value

Reference

PAPm L

1000 nm

Patrushev 2013 [26]

PAPm D

100 nm

Reichenbach 2010 [25]

PAPm volume

7.8539X10^-21 m^3

–

IP3 Dab

300 μm2/s

Kang 2009 [41]

IP3 deagradation

0.8 s

Fink 2001 [38]

PIP2 number in PAPm

3000

Van den Bogaart 2011 and Wang 2012 [30, 31]

[IP3] boundary condition

Constant

–

Maximal [IP3] in PAPm

≈600 μM

–

PLC molecules in PAPm

1, 10, 100

–

PLC specific activity

1000/s-5000/s

Kadamur and Ross 2013 [36]

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BMC Biophysics

ISSN: 2046-1682

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