Fig. 3

Current density and kinetic properties of NavMs expressed in HEK293T cells. a Typical whole cell currents recorded from HEK293 cells transfected to express (i) monomeric, (ii) tetrameric and (iii) trimeric NavMs. (iv) Typical recording from CHO cells expressing trimeric NavMs. Currents were recorded in response to stepping the voltage from 40 mV to − 60 mV in − 20 mV step from a Vhold of − 140 mV. b Mean peak current density from HEK293 cells expressing tetrameric (closed squares; n = 7), and monomeric (open squares; n = 6) NavMs. Error bars represent SEM. c Activation kinetic properties (determined from fitting an exponential power function). Currents result from Vhold of − 140 mV). Error bars represent SEM