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BMC Biophysics


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  1. Content type: Research article

    Cells exhibit distortion when exposed to a strong electric field, suggesting that the field imposes control over cellular biomechanics. Closed pure lipid bilayer membranes (vesicles) have been widely used for ...

    Authors: Hui Ye and Austen Curcuru

    Citation: BMC Biophysics 2015 8:2

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  2. Content type: Research

    The recent developments of far-field optical microscopy (single molecule imaging techniques) have overcome the diffraction barrier of light and improve image resolution by a factor of ten compared with convent...

    Authors: Renmin Han, Liansan Wang, Fan Xu, Yongdeng Zhang, Mingshu Zhang, Zhiyong Liu, Fei Ren and Fa Zhang

    Citation: BMC Biophysics 2015 8:1

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  3. Content type: Research article

    The polyvalent acidic lipid phosphatidylinositol, 4,5-bisphosphate (PIP2) is important for many cellular functions. It has been suggested that different pools of PIP2 exist in the cytoplasmic leaflet of the plasm...

    Authors: Kyu Il Lee, Wonpil Im and Richard W Pastor

    Citation: BMC Biophysics 2014 7:13

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  4. Content type: Methodology article

    Cells continuously undergo DNA damage from exogenous agents like irradiation or genotoxic chemicals or from endogenous radicals produced by normal cellular metabolic activities. DNA strand breaks are one of th...

    Authors: Michael Junk, Judy Salzwedel, Thilo Sindlinger, Alexander Brkle and Maria Moreno-Villanueva

    Citation: BMC Biophysics 2014 7:9

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  5. Content type: Research article

    The complement protein C5a acts by primarily binding and activating the G-protein coupled C5a receptor C5aR (CD88), and is implicated in many inflammatory diseases. The cyclic hexapeptide PMX53 (sequence Ace-P...

    Authors: Phanourios Tamamis, Chris A Kieslich, Gregory V Nikiforovich, Trent M Woodruff, Dimitrios Morikis and Georgios Archontis

    Citation: BMC Biophysics 2014 7:5

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  6. Content type: Correspondence

    A key challenge in interdisciplinary research is choosing the best approach from a large number of techniques derived from different disciplines and their interfaces.

    Authors: Sanford H Leuba, Sean M Carney, Elizabeth M Dahlburg, Rebecca J Eells, Harshad Ghodke, Naveena Yanamala, Grant Schauer and Judith Klein-Seetharaman

    Citation: BMC Biophysics 2014 7:6

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  7. Content type: Research article

    Based on the dynamics of antigen recognition from T cell receptor complex and T cell activation, different function of T cells may present different morphology feature, at least at molecular level. Regulatory ...

    Authors: Xu Wang, Zhenyi Jin, Xinyu Wang, Shaohua Chen, Lijian Yang, Kanger Zhu, Xiuli Wu and Yangqiu Li

    Citation: BMC Biophysics 2014 7:7

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  8. Content type: Research article

    Brownian dynamics (BD) simulations can be used to study very large molecular systems, such as models of the intracellular environment, using atomic-detail structures. Such simulations require strategies to con...

    Authors: Paolo Mereghetti, Michael Martinez and Rebecca C Wade

    Citation: BMC Biophysics 2014 7:4

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  9. Content type: Research article

    Viroids are the smallest pathogens of plants. To date the structural and conformational details of the cleavage of Avocado sunblotch viroid (ASBVd) and the catalytic role of Mg2+ ions in efficient self-cleavage a...

    Authors: Gaston Hui-Bon-Hoa, Hussein Kaddour, Jacques Vergne, Sergei G Kruglik and Marie-Christine Maurel

    Citation: BMC Biophysics 2014 7:2

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  10. Content type: Research article

    Intracellular transport is crucial for many cellular processes where a large fraction of the cargo is transferred by motor-proteins over a network of microtubules. Malfunctions in the transport mechanism under...

    Authors: Donatello Materassi, Subhrajit Roychowdhury, Thomas Hays and Murti Salapaka

    Citation: BMC Biophysics 2013 6:14

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  11. Content type: Research article

    Assembly of the ribosome from its protein and RNA constituents must occur quickly and efficiently in order to synthesize the proteins necessary for all cellular activity. Since the early 1960’s, certain charac...

    Authors: Brittany Burton Lott, Yongmei Wang and Takuya Nakazato

    Citation: BMC Biophysics 2013 6:13

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  12. Content type: Research article

    Keratins are important structural proteins found in skin, hair and nails. Keratin Intermediate Filaments are major components of corneocytes, nonviable horny cells of the Stratum Corneum, the outermost layer o...

    Authors: Anna Akinshina, Etienne Jambon-Puillet, Patrick B Warren and Massimo G Noro

    Citation: BMC Biophysics 2013 6:12

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  13. Content type: Research article

    Increasing applications of titanium dioxide (TiO2) fine particles (FPs) and nanoparticles (NPs) require coupled knowledge improvement concerning their biokinetic effects. Neutrophils are quickly recruited to tita...

    Authors: Everton Luis Santos da Rosa

    Citation: BMC Biophysics 2013 6:11

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  14. Content type: Research article

    PQS (Pseudomonas Quinolone Signal) and its precursor HHQ are signal molecules of the P. aeruginosa quorum sensing system. They explicate their role in mammalian pathogenicity by binding to the receptor PqsR that ...

    Authors: Anke Steinbach, Christine K Maurer, Elisabeth Weidel, Claudia Henn, Christian Brengel, Rolf W Hartmann and Matthias Negri

    Citation: BMC Biophysics 2013 6:10

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  15. Content type: Research article

    Water is essential for life, but some organisms can survive complete desiccation, while many more survive partial dehydration during drying or freezing. The function of some protective molecules, such as sugar...

    Authors: Antoaneta V Popova and Dirk K Hincha

    Citation: BMC Biophysics 2013 6:9

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  16. Content type: Research article

    Drop drying is a key factor in a wide range of technical applications, including spotted microarrays. The applied nL liquid volume provides specific reaction conditions for the immobilization of probe molecule...

    Authors: Jens Sobek, Catharine Aquino, Wilfried Weigel and Ralph Schlapbach

    Citation: BMC Biophysics 2013 6:8

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