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Table 1 Fit parameters for the relative fluorescence intensity

From: Mathematical modelling of the automated FADU assay for the quantification of DNA strand breaks and their repair in human peripheral mononuclear blood cells

Donor

P 0

λ

1

0.79 ± 0.01

0.18 ± 0.02

2

0.74 ± 0.06

0.24 ± 0.04

3

0.64 ± 0.04

0.21 ± 0.03

4

0.65 ± 0.02

0.21 ± 0.02

5

0.51 ± 0.04

0.20 ± 0.05

6

0.65 ± 0.05

0.20 ± 0.04

7

0.60 ± 0.03

0.30 ± 0.04

8

0.63 ± 0.02

0.25 ± 0.02

9

0.66 ± 0.04

0.31 ± 0.05

10

0.74 ± 0.03

0.28 ± 0.02

11

0.66 ± 0.08

0.18 ± 0.06

  1. The zero-dose value P 0 shows a considerable variation among the donors ranging from 0.5 to 0.8, which is roughly three times the typical width of a confidence interval. In contrast, the exponential decay parameter has much less variation in the range 0.18 to 0.31, which amounts only to a single width of the typical confidence intervals.
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BMC Biophysics

ISSN: 2046-1682

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