Table 1 The measured translational diffusion coefficients of dioxane and α-synuclein and the calculated hydrodynamic radius of α-synuclein at different concentration ratios of αS/Lu3+
From: α-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillation
CαS : CLu3+ | Translational diffusion coefficients | Hydrodynamic radius RH (Å) | |
|---|---|---|---|
αS (methyl regoins from 0.87–0.56 ppm) D t × 10−11(m2/s) | Dioxane (3.65–3.53 ppm) D t × 10−10(m2/s) | ||
1 : 0 | 5.802 ± 0.001 | 8.482 ± 0.004 | 30.99 ± 0.05 |
4 : 1 | 5.949 ± 0.004 | 8.610 ± 0.004 | 30.68 ± 0.03 |
2 : 1 | 5.823 ± 0.006 | 8.488 ± 0.004 | 30.90 ± 0.04 |
1 : 1 | 5.845 ± 0.004 | 8.575 ± 0.004 | 31.10 ± 0.03 |
1 : 2 | 5.939 ± 0.003 | 8.626 ± 0.004 | 30.79 ± 0.02 |
1 : 4 | 5.915 ± 0.003 | 8.694 ± 0.005 | 31.16 ± 0.02 |