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Table 2 FoldX predictions of RAS mutation effects for RAS complexes

From: Modeling of RAS complexes supports roles in cancer for less studied partners

RAS Isoform Interaction Partner Mutation Effect
HRAS BCL2 A146T stabilizing
HRAS FHOD1 G12D de-stabilizating
HRAS FHOD1 G13D de-stabilizating
HRAS FHOD1 Q61H stabilizing
HRAS RALGDS G12D stabilizing
HRAS RALGDS G13D stabilizing
HRAS RALGDS A59G stabilizing
KRAS RALGDS G13D stabilizing